We are a highly driven research team. We believe intellectual curiosity and scientific rigor will lead to an ultimate understanding how brain works.

Weifeng Xu

Principal Investigator

Weifeng Xu

Principal Investigator Assistant Professor of Neuroscience
The Picower Institute for Learning and Memory
Department of Brain and Cognitive Sciences
Massachusetts Institute of Technology

Office: 46-4239A
Phone: 617-715-5392
Email: weifeng@mit.edu
Connect: LinkedIn / ResearchGate

Short Biography

Weifeng Xu went to Peking University for her undergraduate education, major in Biophysics and Physiology in the College of Life Sciences. Weifeng Xu did her Ph.D study with Dr. Diane Lipscombe in the Neuroscience Graduate Program at Brown University. Weifeng did her postdoctoral training with Dr. Robert Malenka at Stanford University School of Medicine.
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Laboratory Managers

Yan Liu

Laboratory Manager

Yan Liu

Laboratory Manager / Technical Assistant

M.S. Cell Biology, Kunming Institute of Zoology, Chinese Academy of Sciences, 2007
B.S. Biotechnology, Sichuan University 2004

Office: 46-4239
Phone: 617-452-2695 / 617-715-5413
Email / LinkedIn / Research Gate

Short Biography

I worked as a research associate in Shanghai Institute of Biochemistry and cell biology for two years before I joined the Xu lab in 2010. As a lab manager I manage and control laboratory operations and provide technical support as well. Such as tissue culture, virus preparation and maintenance mouse colonies.

Xiaobai Ren

Laboratory Manager

Xiaobai Ren

Technical Assistant/Lab Manager

Ph.D. in Biophysical Chemistry, Peking University 2011
B.S. in Chemistry, Nankai University 2005

Office: 46-4239
Phone : 617-452-2695
EmailLinkedIn / Research Gate

Short Biography

I am the technical assistant/lab manager helping manage and maintain an efficient workflow in the lab on a daily basis, and providing technical support. I joined Xu’s lab in 2014. I was in structural biology research field, and got my Ph.D. from Beijing NMR Center.

Postdoctoral Researchers

Kendrick Jones

Postdoctoral Associate

Kendrick Jones

Postdoctoral Associate

Ph.D. Yale University, Molecular Cellular and Developmental Biology, 2007
B.S. Brown University, Biology 2000

Office: 46-4267
Phone: 617-715-5413
Email

Short Biography

As a postdoc in the Xu lab I study in the regulation of a protein, Neurogranin, which plays an important role in regulating calcium signaling events in neurons. Specifically I am interested in how rapid changes in the concentration of Neurogranin within neurons can regulate memory formation in the hippocampus. I use a variety of biochemical, cell biological, and behavioral assays to address questions about the role of new protein synthesis in learning and memory.

Kyung Seok Han

Postdoctoral Associate

Kyung Seok Han

Postdoctoral Associate

Ph.D. UST/KIST, Neuroscience, 2013
B.S. Yonsei University, Biology, 2007

Office: 46-4267
Phone: 617-715-5413
EmailLinkedIn / ResearchGate

Short Biography

During my first two years of the doctoral program, I researched the inhibition of the invasion of glioblastoma by caffeine using electrophysiology, biochemistry, and Ca2+ imaging techniques. After that, I became interested in the role of gliotransmitters from astrocyte in brain function. My previous study was neuron-glia interaction in opioid addiction and was the focus of my Ph.D thesis.

Graduate Students

Sebastian Templet

Graduate Student

Sebastian Templet

Graduate Student

M.S. Applied Cognition and Neuroscience
B.S. Biochemistry
B.S. Neuroscience

Office: 46-4267
Phone: 617-715-5413
EmailLinkedIn / ResearchGate

Short Biography

I developed an early interested in Neuroscience and earned my degrees from the University of Texas at Dallas where I studied hippocampal function in a rat model of tinnitus while also learning how to construct recording electrodes for in vivo recordings in freely-behaving rats. At MIT, I became interested in how small molecular changes can alter network level interactions in hippocampal circuitry and lead to plasticity.

Hongik Hwang

Graduate Student

Hongik Hwang

Graduate Student

Ph.D. Candidate
B.S. Chemistry, POSTECH, South Korea

Office: 46-4267
Phone: 617-715-5413
Email / LinkedIn / ResearchGate

Short Biography

Hongik is interested in the molecular mechanisms of synaptic plasticity underlying memory formation in the Xu lab. In particular, he aims to decipher how calcium signaling in postsynaptic compartments plays a role in the induction of long-term potentiation in the hippocampus. A current focus of his study is a small neuron-specific protein, neurogranin, which is thought to regulate the availability of calmodulin for calcium binding in neurons.

Undergraduate Students

Fancisco Pena

Undergraduate Student

Fancisco Pena

Undergraduate Student

Candidate for BS in Brain and Cognitive Sciences

Office: 46-4267
Phone: 617-715-5413
EmailLinkedIn / ResearchGate

Short Biography

As a researcher, I’m interested in memory formation at the cellular level. When the hippocampus first begins to encode a memory many, but not all, cells will be activated as part of a memory trace. Why do some neurons take part in the memory trace and some don’t? How do intracellular signals determine the likelihood of a neuron to become part of a memory trace? I’m developing an independent project to work on this line of investigation and that is one of the greatest parts of working in Weifeng’s lab.

Rebecca Shi

Undergraduate Student

Rebecca Shi

Undergraduate Student

Candidate for B.S. in Biology and Brain and Cognitive Sciences

Office: 46-4267
Phone: 617-715-5413
EmailLinkedIn / ResearchGate

Short Biography

Rebecca is an undergraduate working as a UROP in the Xu Lab. She uses primarily biochemistry and electrophysiology to study the Shank proteins at synapses in the hippocampus, and is interested in how the Shank proteins regulate synaptic transmission. Outside the lab, she participates in MIT’s fencing team and enjoys bird watching when she can.

Lei Ding

Undergraduate Student

Lei Ding

Undergraduate Student

Undergraduate in Course 6/7, Computational Biology

Office: 46-4267
Phone: 617-715-5413
Email

Short Biography

I have been fascinated by the mechanisms of the mind for many years. Throughout high school, I explored biology of all types, but neuroscience still held a special attraction for me. At MIT, I am integrating both my dreams by studying to earn a degree in computational biology while doing research on neuroprotection from exicotoxicity in Professor’s Xu’s lab.

Raymond Liu

Undergraduate Student

Raymond Liu

Undergraduate in Course 20, Bioengineering

Office: 46-4267
Phone: 617-715-5413
Email / LinkedIn / ResearchGate

Short Biography

Raymond Liu is an undergraduate from Northern California who joined the Xu lab in the fall of 2013. Raymond’s current research explores the phosphorylation states of various proteins under different levels of Neurogranin in dissociated neuron culture. Raymond is excited to be in a lab that looks at the phenomena of learning of memory from both biochemical and behavioral levels.