Our goal is to understand mechanisms of neural plasticity essential for information processing and storage in the brain and their dysfunction in diseases such as autism, schizophrenia, bipolar disorder and mental retardation.
We are interested in understanding how signaling scaffolds in the postsynaptic compartment of neurons organize and orchestrate signaling events that lead to the expression of synaptic plasticity important for learning and memory.
We are also interested in understanding how regulating calcium homeostasis via activity-dependent mechanisms modulates synaptic plasticity and neuronal excitability; consequently modulate animals’ learning ability.
Xu Laboratory is looking for passionate, highly motivated, ambitious and creative young scientists to be part of our team.
We are currently accepting application for the following open positions:
- Postdoctoral Associates & Fellows
- Graduate Students
- Laboratory Manager
- Undergraduate Research Opportunities
- Bjartman L, Huberman AD, Ullian EM, Renterfa RC, Liu X, Xu W, Stellwagen D, Prezioso J, Stokes C, Cho R, Worley P, Malenka RC, Ball S, Peachey NS, Copenhagen D, Chapman B, Nakamoto M, Barres BA, Perin M. (2006). Neuronal pentraxins mediate synaptic refinement in the developing visual system. J Neurosci, 26: 6269-6281 PMID: 16763034. View PDF » Journal Link »
* these authors contributed equally to this work.
- Contributing Author, Molecular Neuropharmacology (2nd Edition) Chapter 3: Electrical Excitability of Neurons.